Biomedical Engineering, Duke University

137 11276
Position ID:Duke-BME-CELLANDGENETHERAPIESPOSTDOC [#11276, Bursac Postdoc3]
Position Title: Postdoctoral Fellow in Cell and Gene Therapies for Cardiac Arrhythmias and Heart Failure
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27708, United States [map]
Subject Area: Biomedical Engineering / Molecular and cellular systems
Appl Deadline:2019/03/01 (posted 2018/06/07, listed until 2019/03/01)
Position Description:    

Postdoctoral Fellow in Cell and Gene Therapies for Cardiac Arrhythmias and Heart Failure

Postdoctoral opening in gene- and cell-based therapy for cardiac arrhythmias and heart failure are immediately available in Bursac lab ( We are looking for highly motivated candidates with expertise in single cell and tissue-level electrophysiology, cell and molecular biology, and small or large animal models of heart disease. The project will aim to develop novel cell- and gene-based therapies for cardiac arrhythmias and heart failure and will include patch clamp studies and mutagenesis of ion channels, viral genetic manipulations of excitable and unexcitable cells, and application of tissue and genetic engineering techniques to improve electrical conduction, prevent or terminate arrhythmias, and augment contractile function of acutely injured or chronically diseased hearts. Ventricular arrhythmias, atrial fibrillation, conduction system disease, and heart failure will be the main therapeutic targets of this work.

Qualifications include PhD and/or postdoctoral experience in single cell (patch clamp, sharp electrode) and tissue/organ cardiac electrophysiology, molecular biology, genetics, and other relevant areas of biomedical sciences. The ideal candidate will be highly self-motivated and possess strong training in electrophysiology, molecular biology, animal studies, biochemical and histological assays. Experience in optical mapping of action potentials in the heart and work with transgenic animals is a plus. Postdoctoral fellows are expected to publish research findings in peer-reviewed journals, participate in conferences for the intellectual exchange of research ideas, engage in existing and new collaborations within and outside Duke University, and assist with training of undergraduate and graduate students, as needed. The training environment of the Bursac group is highly interdisciplinary and provides ample opportunities for scientific growth and pursuit of both academic and industry careers. Duke University is an equal opportunity employer. Interested candidates should send their resume, statement of research goals, and names of three reference writers to Dr. Nenad Bursac (

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status. Duke also makes good faith efforts to recruit, hire, and promote qualified women, minorities, individuals with disabilities, and veterans.

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