Molecular Biology & Genetics, Cornell University

Position ID:Cornell-MBG-POSTDOCAQUADROLAB [#11553, WDR-00015965]
Position Title: Postdoctoral Research Associate
Position Location:Ithaca, New York 14853, United States [map]
Subject Areas: Genetics
Developmental Biology
Genomics
Appl Deadline:2018/12/31 (posted 2018/08/02, listed until 2018/12/31)
Position Description:    

The appointment is expected to begin as early as September 4, 2018.

Position Function

A successful candidate will help design and carry out research aimed at testing evolutionary and functional hypotheses to explain the episodic positive selection on the bam gene in different species of the fruit fly genus Drosophila. An ability to integrate population genetic and functional genomic approaches is key.  Work will focus on experimental studies:  CRISPR/Cas9 genome editing and the analysis of fertility, cytological and gene expression for edited variants in multiple species of Drosophila. Good “hands” in the lab are critical as is attention to detail and accuracy. 

Anticipated Division of Time

The main responsibilities include conducting research, attending lab meetings and journal clubs, and preparing research results for publication and presentations at scientific meetings. Opportunities may also exist for mentoring graduate and undergraduate students.


Requirements

Minimum/Basic Qualifications (required by start date):

- PhD or equivalent degree in genetics, developmental biology, population genetics functional genomics, or a related field.

- Demonstrated record of research productivity and publications.

- Strong molecular biology skills

 

Preferred Qualifications:

- Research experience with Drosophila genetics and/or developmental biology.

- Experience with CRISPR/Cas9 genome editing or a strong desire to learn.

- Knowledge of or willingness to earn at least basic population genetics theory.

- Experience with fluorescent microscopy

- Experience with genomic data analysis.

- Programming/scripting experience or a willingness to learn (e.g. Python/ Perl, R)

Our lab’s current research focus is on the population genetics and evolution of genes that regulate germ line stem cells in Drosophila.  Our focus is the evolutionary and functional analysis of bag of marbles (bam), the key regulatory “switch” gene for germ line stem cell renewal or differentiation in Drosophila. Our work involves the use of CRISPR/Cas9 genome editing to functional test hypotheses of protein function and evolutionary drivers of strong positive natural selection we discovered acting on bag of marbles in multiple species and lineages of Drosophila. Central to our studies are tests of functional and evolutionary interaction of the intracellular bacteria Wolbachia and germ line stem cell genes, particularly bag of marbles, across the genus Drosophila.  We are also carrying out computational analyses of the evolutionary history of Wolbachia infections in Drosophila species.

Salary: This is a full-time position. Salary is commensurate with qualifications and experience and consistent with the current NIH postdoc salary scale and your level of experience..

How to apply:

Applicants should submit the following materials:

- A cover letter

- A curriculum vitae

- One page statement of your research accomplishments

- One-page statement of your specific interests and qualifications for this position and why you feel you are an excellent fit.

- Contact information for 3 references.  Letters of reference are not required at this time.

 

This position will be open until filled. The earliest start date is September 4 2018. The appointment is for a duration of one year with the possibility of annual renewal up to three years. Please address inquiries to Chip Aquadro  cfa1@cornell.edu


 



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Application Materials Required:
Submit the following items online at this website to complete your application:
And anything else requested in the position description.

Further Info:
https://mbg.cornell.edu
email
607-255-2317
 
Molecular Biology & Genetics

107 Biotechnology Building
526 Campus Road
Cornell University
Ithaca, NY 14853-2703

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