Duke University, Molecular Genetics and Microbiology

Position ID:Duke-MGM-SILVERPOSTDOC [#12109]
Position Title: Postdoctoral Associate
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27710, United States [map]
Subject Areas: Biology
Appl Deadline: finished (2018/09/24, finished 2018/12/12)
Position Description:    

*** this position has been closed. ***

Due to change in processing systems all applicants interested in the available position must apply online at


Postdoctoral Position

Silver Lab

Duke University Medical Center

The Silver lab at Duke University School of Medicine seeks a highly motivated postdoctoral research fellow for a funded position to investigate RNA localization and local translation in the developing brain. Our lab recently discovered that RNA is actively transported to distal compartments of neural stem cells in the developing brain, where it is locally translated (Pilaz et al, Current Biology, 2016; Pilaz and Silver, FEBs Letters, 2017).  These discoveries establish a new in vivo paradigm for studying local regulation of gene expression and for investigating new biological processes within neural stem cells. The postdoctoral fellow will have the exciting opportunity to implement and integrate cutting edge approaches in transcriptomics, live imaging, RNA biology and cortical development. 


The successful applicant will have a strong and productive scientific record, be highly collaborative, diligent, and have previous experience in one or more of the relevant fields: RNA biology, developmental neurobiology, and mouse genetics.


The Silver lab investigates genetic and cellular mechanisms controlling cerebral cortex development, and contributing to neurodevelopmental pathologies and brain evolution. To tackle these questions we employ mouse genetics and embryology, fixed and live imaging of embryonic brain slices and neural progenitors, and genomics. The lab collaborates with RNA biologists, stem cell biologists, and developmental neurobiology labs at Duke and is a member of the Center for RNA Biology, Regeneration Next Initiative, and Duke Institute for Brain Sciences. Our lab offers a vibrant and rigorous training environment for postdoctoral fellows.


Our other recent accomplishments include: discovery of novel post-transcriptional mechanisms controlling neural progenitor function and contributing to microcephaly (Pilaz, McMahon et al, Neuron, 2016; Mao, McMahon et al, PLOS Genetics, 2016; Mao et al, J. Neuroscience, 2015) and discovery of genetic mechanisms relevant for brain evolution (Boyd et al, Current Biology, 2015; Silver, Bioessays, 2016). Please see: https://sites.duke.edu/silverlab/


Candidates must apply online to this position to be considered.  

Duke is committed to encouraging and sustaining work and learning environments that are free from harassment and prohibited discrimination. Duke prohibits discrimination and harassment in the administration of both its employment and educational policies. Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, genetic information, gender, gender expression, gender identity, national origin, race, religion, sex, sexual orientation, or veteran status. Duke also makes good faith efforts to recruit, hire, and promote qualified women, minorities, individuals with disabilities, and veterans.

This employer is not accepting applications for this position through AcademicJobsOnline.Org. Please see the job description above on how to apply.
Contact: Debra Silver, PhD, 919-668-7909, 919-684-2790 (fax)
Email: email
Postal Mail:
224 CARL Building
Box 3175 DUMC
Durham, N.C. 27710
Web Page: https://sites.duke.edu/silverlab/

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