The Tata lab in the Department of Cell Biology, Duke University School of Medicine has two openings for postdoctoral researchers to study cellular plasticity mechanisms in lung injury repair and tumorigenesis. We seek to understand the genetic and epigenetic basis of organ regeneration and tumorigenesis. We study the properties of stem/progenitor cells in diverse epithelial tissues (with a primary focus on lung) and their relationships with neighboring tissues in pathophysiological conditions. We utilize in vivo mouse genetics, live imaging, 3D organoids, genome-wide Cas9/Crispr based functional genetic screening, and next generation sequencing technologies to study the behavior of tissues at single cell level. We offer an inspiring intellectual, collaborative and multidisciplinary research environment to support your career goals and provide access to state-of-the-art facilities. Candidates with background knowledge and hands-on experience in transcriptional regulation, 3D-organoids and bioinformatics skills are particularly welcome.
Requirements
- A PhD or MD/PhD (or equivalent) in biological sciences (cell & developmental biology or a related field).
- Strong research background in transcriptional regulation, cell biology, molecular biology, mouse models of cancer, and/or biochemistry. Prior experience in stem cells, Cas9/Crispr gene editing, 3D-organoid cultures, chromatin biology and bioinformatics is advantageous.
- Evidence of successful completion of a research project (publications)
- Ability to work independently; interpret, present and discuss experimental data
- Excellent communications skills
To apply, please submit a cover letter (less than a page) that includes a short summary of interests, a CV, and the contact information of 3 professional references to Dr. Purushothama Rao Tata (purushothamarao.tata@duke.edu)
Applications will be reviewed until positions are filled. The positions are available immediately.
Relevant literature:
1. Tata P.R. et al., Nature, 2013
2. Pardo. A*, Tata P.R.* et al., Nature, 2015
3. Tata A. et al., Cell Stem Cell, 2018
Duke is an Affirmative Action / Equal Opportunity Employer committed to providing employment opportunity without regard to an individual’s age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status. |
finished (offers accepted 2019/01/24, finished 2019/10/06)