Cornell University, Biomedical Engineering

Position ID:Cornell-BME-RESEARCHASSOCIATE [#15460,]
Position Title: Research Associate (Genomics-based Medicine Technologies)
Position Type:Other
Position Location:Ithaca, New York 14853, United States [map]
Subject Areas: Biomedical Engineering / Biochemistry, Bioinformatics, Molecular Biology, genome engineering technologies
Appl Deadline:none (posted 2019/11/12)
Position Description:    

*** the list date or deadline for this position has passed, and no new applications is accepted. ***

Research Associate Position (Genomics-based medicine technologies for the diagnosis of infectious and immune related disease)

A position for a research associate is available in the group of Iwijn De Vlaminck at Cornell University. This will be a two-year appointment, with possible extension based on performance.

The research in the De Vlaminck lab is focuses on the development of genomics-based medicine technologies to study and diagnose infectious and immune related disease in humans.

Of immediate interest to the available position, the lab is pursuing the phenomenon of circulating cell-free DNA, small fragments of DNA that can be isolated from blood and urine, as an analyte for the diagnosis of infection and immune injury. The candidate will play a central role in multiple, multi-PI, collaborative projects with the goal to 1) Test the utility of cell-free DNA in urine as an analyte to monitor urinary tract infection. 2) Test the utility of a measurement of the tissues-of-origin of cell-free DNA in the blood circulation to monitor post-transplant immune complications. 3) Test the utility of cell-free DNA in blood or urine to monitor or screen tuberculosis. These research directions are supported by multiple grants from the National Institutes of Health, and the Bill and Melinda Gates Foundation.

Representative research articles: 1. A cell-free DNA metagenomic sequencing assay that integrates the damage response to infection. Alexandre Pellan Cheng, Philip Burnham, John Richard Lee, Matthew Pellan Cheng, Manikkam Suthanthiran, Darshana Dadhania, Iwijn De Vlaminck Proceedings of the National Academy of Sciences (2019).

2. Urinary cell-free DNA is a versatile analyte for monitoring infections of the urinary tract Philip Burnham, Darshana Dadhania, Michael Heyang, Fanny Chen, Manikkam Suthanthiran, John Richard Lee*, Iwijn De Vlaminck* Nature Communications (2018).

3. Circulating Cell-Free DNA Enables Noninvasive Diagnosis of Heart Transplant Rejection Iwijn De Vlaminck, Hannah A. Valantine, Thomas M. Snyder, Calvin Strehl, Garrett Cohen, Helen Luikart, Norma F. Neff, Jennifer Okamoto, Daniel Bernstein, Dana Weisshaar, Stephen R. Quake, and Kiran K. Khush Science Translational Medicine, 6, 241ra77 (2014)

Candidates are required to hold Ph.D or M.D./Ph.D. degrees (or expected to soon obtain Ph.D or M.D./Ph.D. degrees) and to have at least two years of equivalent postdoc associate experience. The candidate will have a track record of publications in leading journals. Preference will be given to technically skilled and creative researchers that can effectively communicate with clinical collaborators. Prior experience with bioinformatics and/or molecular biology is desirable but not required. Candidates with a research background in unrelated fields (e.g. biophysics, physics, chemistry), but that possess exceptionally strong quantitative skills are encouraged to apply.

The successful candidate will have fluency in written and spoken English and ability to work well with other stakeholders.

Diversity and Inclusion are a part of Cornell University’s heritage. We are a recognized employer and educator valuing AA/EEO, Protected Veterans, and Individuals with Disabilities.

Application Materials Required:
Submit the following items online at this website to complete your application:
And anything else requested in the position description.

Further Info:
Cornell University
Department of Biomedical Engineering
115 Weill Hall
Ithaca, NY 14853-7202

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