• Develop and utilize technology for analyzing signal transduction in vitro and in vivo.

• Develop and utilize novel and existing mouse models of head and neck squamous cell carcinoma.

• Perform PCR for genotyping mice and evaluating recombination of conditional alleles from genetically engineered mouse models.

• Care for laboratory mice including breeding and providing supportive care.

• Perform cytotoxicity and clonogenic assays in vitro to evaluate effects of drugs and genetic modifications on radiation sensitivity of cell lines.

• Develop and optimize radiation treatment plans for head and neck squamous cell carcinoma mouse models and normal tissue radiation toxicity experiments.

• Organize overall research plan and design, execute, and troubleshoot individual experiments.

• Maintain an organized and complete laboratory notebook detailing all experiments in electronic format utilizing Lab Archives.

• Meet with PI regularly and keep PI informed of all important positive and negative results.

• Keep equipment operating by following operating instructions; troubleshooting breakdowns; maintaining supplies; performing preventive maintenance; calling for repairs.

• Maintain safe and healthy work environment by complying with regulations and following standards and procedures.

• Prepare manuscripts for scientific publication with PI supervision.

• Assist with preparation of grant applications.

• Protect organization's value by keeping research information confidential.

• Update job knowledge by participating in educational opportunities, networking and presenting at local, national and international meetings, and reading current primary literature.

• Provide a friendly working environment and be available to teach research technicians and other trainees laboratory techniques and scientific methodology.

• Min Degree Requirements:

• · Ph.D.or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.).

• · Should be used for post-doctoral fellows if the candidate has completed all of the requirements for a degree, but the degree has not been formally conferred; the candidate may present evidence of completion of the degree requirements, together with a statement documenting the date on which the degree is to be conferred.

• Other Credential/Experiential Requirements:

• The incumbent must be a true post-doctoral fellow registered with the Post Doc Office and per the following requirements:

• · The term of this appointment is limited (5 years with a possible extension for an additional year)

• · The appointment involves substantially full-time research or scholarship, which may include teaching responsibilities.

• · The appointment is viewed as preparatory for a full time academic or research career.

• · The appointment is not part of a clinical research training program, unless research training under the supervision of a senior mentor is a primary purpose of the appointment.

• · The appointee works under the supervision of a scholar or a department at Duke University.

• · The appointee has the freedom, and is expected to publish the results of his or her research or scholarship during the period of the appointment.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.