Duke University, Center for Advanced Genomic Technologies

5178 23725
Position ID:Duke University-Center for Advanced Genomic Technologies-PDMODELS [#23725, 0027]
Position Title: Postdoctoral Fellow in Genome Engineering Technologies to Treat Models of Disease
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27708, United States
Subject Area: Biomedical Engineering / Biomedical Engineering
Appl Deadline:2023/03/31 11:59PMhelp popup (posted 2022/11/15, updated 2022/12/07, listed until 2023/05/14)
Position Description:    

Postdoctoral Fellow in Genome Engineering Technologies to Treat Models of Disease

An opening for a postdoctoral fellowship position focused on genome and epigenome editing-based therapies for models of human diseases is immediately available in the Gersbach Lab at Duke University, Pratt School of Engineering, Department of Biomedical Engineering (http://gersbach.bme.duke.edu). We are looking for a highly motivated candidate with expertise in gene delivery, regeneration, epigenetics, cell and molecular biology, genetics, and other relevant areas of biomedical sciences. The project will aim to investigate the development of gene therapies for human disease using CRISPR technologies, and modeling of human disease using induced pluripotent stem cells (iPSCs).

The successful applicant will lead projects on developing methods for delivery of CRISPR tools in vivo, studying effects of CRISPR delivery in various cells and tissues, understanding barriers to effective delivery, identifying causal molecular mechanisms for initiation and inheritance of gene expression at human disease-related loci, and developing a targeted approach using CRISPR technologies for persistent gene modulation. We are particularly interested in candidates with expertise in viral and nonviral delivery systems, genome and epigenome editing; CRISPR-based disease modeling; protein engineering; and/or high-throughput genetics, genomics, or epigenetics studies. The postdoctoral fellow will work with a collaborative and interdisciplinary team of faculty, postdoctoral associates, graduate and undergraduate students conducting research and training on human gene regulation and gene therapy. The postdoctoral fellow is expected to publish research findings in peer-reviewed journals, participate in conferences for the intellectual exchange of research ideas, engage in existing and new collaborations within and outside Duke University, and assist with training of undergraduate and graduate students, as needed. The training environment of the Gersbach group is highly interdisciplinary and provides ample opportunities for scientific growth and pursuit of both academic and industry careers. Duke University is an equal opportunity employer.

Applicants must have completed their doctoral degree and have documented experience in one or more areas described above. The ideal candidate will be highly self-motivated and will also have a demonstrated track record of scientific productivity, for example via published manuscripts and/or fellowship funding; experience analyzing data from biological experiments; and is excited to work in a highly collaborative and multi-disciplinary research environment. This position includes annual support with an NIH award-level salary, and Duke University employee benefits (https://www.hr.duke.edu/benefits/).

Regularly ranked among the best research institutions in the US, Duke University offers an outstanding research environment and world class training programs. The laboratory is located within the beautiful Duke University west campus, in Durham North Carolina. The research program associated with this project will provide exposure to cutting-edge science and technologies in the areas of genetics, gene therapy, stem cell biology, and human disease that will be greatly valuable to diverse areas of academic research and biotechnology.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Interested candidates should apply at AJO website and send their resume, statement of research goals, and names of three reference writers to gersbachlabjobs@gmail.com.



Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Application Materials Required:
Submit the following items online at this website to complete your application:
And anything else requested in the position description.

Further Info:
http://gersbach.bme.duke.edu
email
 
101 Science Drive
PO Box 90281
Durham, NC 27708