Molecular Genetics and Microbiology, Duke University

Position ID:Duke-MGM-SILVER72017 [#9435]
Position Title: Postdoctoral Associate
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27710, United States [map]
Subject Areas: Virology
Neurobiology / developmental neurobiology
Biology / Mouse Genetics
Appl Deadline: finished (posted 2017/07/27, finished 2018/07/29, listed until 2018/01/22)
Position Description:    

*** this position has been closed, and no new applications will be accepted. ***

The Silver lab at Duke University School of Medicine seeks a highly motivated postdoctoral research fellow to investigate genetic and viral causes of microcephaly. The successful applicant will have a strong and productive scientific record, be highly collaborative, inquisitive, diligent, and have previous experience in one or more of the relevant fields: virology, developmental neurobiology, mouse genetics, and RNA biology.

The Silver lab investigates genetic and cellular mechanisms controlling cerebral cortex development, and contributing to neurodevelopmental pathologies and brain evolution. To tackle these questions we employ mouse genetics and embryology, fixed and live imaging of embryonic brain slices and neural progenitors, and genomics. The Silver lab has ongoing collaborations with expert virologists and RNA biologists in the Department as well as with other developmental neurobiology labs at Duke.

Our recent accomplishments include: discovery of novel post-transcriptional mechanisms controlling neural progenitor function and contributing to microcephaly (Pilaz et al, Current Biology, 2016; Pilaz, McMahon et al, Neuron, 2016; Mao, McMahon et al, PLOS Genetics, 2016; Mao et al, J. Neuroscience, 2015) and discovery of new genetic mechanisms relevant for brain evolution (Boyd et al, Current Biology, 2015; Silver, Bioessays, 2016).

The primary goal for this position will be to investigate the underpinnings of how ZIKA virus infection impairs fetal brain development. The postdoctoral fellow will implement cutting edge technologies in both brain development and virology. Additionally the fellow will have the opportunity to pursue complementary projects in the lab at the intersection of RNA biology and brain development. The lab and Department offer a vibrant and rigorous training environment for postdoctoral fellows.

Candidates must apply online to this position to be considered.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status. Duke also makes good faith efforts to recruit, hire, and promote qualified women, minorities, individuals with disabilities, and veterans.

Application Materials Required:
Submit the following items online at this website to complete your application:
And anything else requested in the position description.

Further Info:
(919) 668-7909
224 CARL Building
Box 3054 DUMC
Durham, N.C. 27710

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