Duke University, Biomedical Engineering

137 26702
Position ID:Duke-BME-DUKEBURSAC2 [#26702]
Position Title: Postdoctoral Associate
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27708, United States [map] sort by distance
Subject Areas: Engineering / Biomedical
Biomedical Engineering / Biomedical Engineering
Appl Deadline: (posted 2023/11/22, listed until 2024/05/22)
Position Description:    

*** the listing date or deadline for this position has passed and new applications are no longer accepted. ***

Postdoctoral Fellow in Heart Regeneration and Repair

An opening for Postdoctoral Fellow in Heart Regeneration and Repair is immediately available in the Bursac group (http://bursaclab.pratt.duke.edu/). The main topic of the project is discovery and application of novel factors and methods that can induce endogenous heart repair via cardiomyocyte proliferation. We are looking for a talented postdoctoral fellow with expertise in cardiac cell biology, physiology, and culture of human iPSC-derived and neonatal rat ventricular myocytes to perform basic and applied studies in the field of cardiac regeneration and repair. The project will involve studies in cultured cardiomyocytes aimed at discovery of processes and factors that stimulate cardiomyocyte dedifferentiation, proliferation, maturation, and regeneration. Furthermore, in vitro discovered and validated cardiomyocyte mitogens will be tested as a gene therapy in rodent and porcine models of myocardial injury. Mechanistic studies of cardiomyocyte cell cycle will be complemented with physiological measurements of cardiac electrical and mechanical function from single cell to tissue and whole-organ levels.

Qualifications include PhD in cell and developmental biology, biomedical and tissue engineering, or other relevant areas of biomedical sciences. The applicant is required to have experience in human iPSC culture, cardiomyocyte differentiation, and good knowledge of cardiac biology, physiology, and tissue engineering. Candidates with expertise in molecular biology, biochemistry, genome editing (CRISPR/Cas9), cardiac physiological measurements, and animal experimentation will be given priority. The candidate needs to be highly motivated, creative, hardworking, a good communicator, and able to work as a part of the team. Our group provides a stimulating and diverse environment with excellent opportunities for scientific growth and pursuit of academic and industry careers. Interested candidates should apply with their resume, statement of research goals, and at least two names for letters of recommendation by writing to Dr. Nenad Bursac (nbursac@duke.edu).

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

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