Cornell Laboratory for Accelerator-based Sciences and Education, Cornell University

Position ID:Cornell-CLASSEPhysics-POSTDOCCHESS [#8787]
Position Title: Postdoc CHESS
Position Type:Other
Position Location:Ithaca, New York 14853, United States [map]
Subject Area: Physics
Appl Deadline: (posted 2017/01/09, listed until 2017/07/09)
Position Description:    

Postdoctoral Associate in Biomolecular Studies - CHESS

The Cornell High Energy Synchrotron Source (CHESS) at Cornell University is seeking a Postdoctoral Associate to use X-ray methods to study the effects of high pressure on biomolecules. The candidate will join a strong and growing community seeking to better understand biomolecular conformational changes and illuminate the molecular basis for pressure resistance of biomolecules from piezophilic organisms. Small-angle X-ray Scattering (SAXS) and crystallography methods will be used to characterize the structural properties of folding intermediates versus unfolded states as well as the role of ions and hydration in stabilizing tRNA structures, for instance. We expect pressure-jump kinetic experiments will yield exciting new insights into transition state volumetric properties of biomolecules.

The successful candidate will lead efforts to adapt CHESS experimental stations for high pressure SAXS and crystallography of proteins and RNA, as well as design approaches to characterize biomolecular folding and function. This position is located at Cornell University in Ithaca, New York, and will collaborate closely with research groups of Drs. Catherine Royer at Rensselaer Polytechnic Institute and Sol Gruner at Cornell. We seek applicants with a PhD in physics, chemistry, biophysics or comparable field, and experience using X-ray, high-pressure and/or biological methods. Required is a willingness to learn new skills as needed and a demonstrated record of hands-on building and optimizing of scientific equipment.

The initial appointment will be for one year, with the expectation of renewal on a yearly basis with satisfactory performance for an additional two years. Applications should be formally submitted at and include a cover letter, CV, and a detailed summary of research experience and interests. Applicants must arrange to have at least three letters of recommendation uploaded, as per instructions on the academicjobsonline website. For technical information about the position, contact Professor Sol M. Gruner, For administrative information contact Ms. Monica A. Wesley,

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Application Materials Required:
Submit the following items online at this website:
And anything else requested in the position description.

Further Info:
134 Newman Lab
Cornell University
Ithaca, NY 14853

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