Duke University, Biomedical Engineering

137 13398
Position ID:Duke-BME-PD4 [#13398, Bursac Postdoc4]
Position Title: Postdoctoral Fellow in Heart Regeneration and Repair
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27708, United States [map]
Subject Areas: Biomedical Engineering / Cardiac arrhythmia and/or heart failure, Cellular Engineering, Regenerative engineering in medicine, Stem Cell Biology, Tissue Engineering and Regenerative Medicine, Genetic Engineering
Appl Deadline:2019/07/01 (accepting applications )
Position Description:    

*** the list date or deadline for this position has passed, and no new applications will be accepted. ***

* this map is a best-effort approximation. Open in Google Maps directly.

Postdoctoral Fellow position in Heart Regeneration and Repair is immediately available.

Our group (http://bursaclab.pratt.duke.edu/) has developed robust methods to generate highly functional human heart tissues made of hiPS cells for use in drug development, disease modeling, and cardiac regenerative therapies. We are looking for a talented postdoctoral fellow with expertise in cardiac cell biology, physiology, and differentiation of human iPSCs to pursue basic experimental studies and therapeutic applications of human engineered heart tissues. The project will involve in vitro studies in human iPSC derivatives aimed at stimulating cardiomyocyte maturation, hypertrophy, proliferation, and regeneration and understanding the roles that cardiomyocyte-nonmyocyte interactions play in these processes. Furthermore, engineered human heart tissues will be implanted and tested for the ability to exert or undergo repair in rodent and porcine models of cardiac injury. Basic biology studies will be complemented with physiological measurements of cardiac electrical and mechanical function at a variety of spatial scales from a single cell to tissue and whole organ. This work is a part of a collaborative project involving cardiac biologists, bioengineers, and clinical scientists.

Qualifications include PhD in developmental and cell biology, biomedical engineering, or other relevant areas of biomedical sciences. The applicant is required to have experience in human stem cell culture, cardiomyocyte differentiation, and good knowledge of cardiac biology and physiology. Expertise in modern techniques of genetic engineering (CRISPR/Cas9), molecular biology, cardiac physiological measurements and animal experimentation are highly desired. The candidate needs to be self-motivated, independent, good communicator, and able to work within a large team of scientists with diverse backgrounds. Our group provides a stimulating environment with excellent opportunities for scientific growth and pursuit of academic and industry careers.

Interested candidates should apply with their resume, statement of research goals, and at least three names for letters of recommendation by writing to Dr. Nenad Bursac (nbursac@duke.edu).

Duke is an Affirmative Action / Equal Opportunity Employer committed to providing employment opportunity without regard to an individual’s age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.


Application Materials Required:
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Further Info:
http://www.bme.duke.edu
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http://www.bme.duke.edu

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