Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center. The candidate should have a doctoral degree such as MD or PhD or equivalent degree and has interests in cancer biology. The research involves understanding the role of mitochondria in multiple myeloma pathogenesis and developing immunotherapy (checkpoint inhibitors and CAR T) and novel agents for the treatment of multiple myeloma. The overall duties and responsibilities are: 1) to develop novel approaches for treating multiple myeloma; 2) to perform experiments and collect data, and to evaluate experimental data and establish the relevance to experimental problems under investigation; 3) to prepare research results for publication in reports, papers, journals, books, and other media; and 4) to train and direct support personnel. The candidates are expected to have training or experience in genetically modified mouse models, animal bone marrow transplant models, flow cytometry, immunohistochemical staining, and lentiviral-based gene transfer. Prior experiences in confocal microscope and electronic microscope techniques are a plus.
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