Duke University, Radiation Oncology/Research Labs

Position ID:Duke University-Radiation Oncology/Research Labs-POSTDOC [#21353, 3820]
Position Title: Postdoctoral Associate
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27712, United States [map]
Subject Area: Biology / Molecular
Appl Deadline:2022/06/30 11:59PMhelp popup (posted 2022/03/08, listed until 2022/06/30)
Position Description:    

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Postdoctorial Associate (3820) Duties (Reitman Lab)

The goal of the Reitman Lab (https://radonc.duke.edu/research/reitman-lab ) is to make discoveries that guide the design of improved treatment strategies for children and adults with brain tumors. We leverage molecular biology techniques, genetically engineered mouse models and cancer genomic approaches to carry out our work. The Reitman Lab is based in the Department of Radiation Oncology and the team works closely with the faculty and staff in the Preston Robert Tisch Brain Tumor Center at Duke, the Department of Neurosurgery and the Duke Cancer Institute. We are interested in several research themes, including:

(1) Using primary genetically engineered mouse models of pediatric and adult brain tumors to study mechanisms of tumorigenesis, mechanisms of treatment resistance, and candidate therapeutic strategies.

(2) Identifying new therapeutic dependencies associated with frequent cancer mutations.

(3) Identifying methods to increase the efficacy and decrease toxicity of radiation therapy for brain tumor patients.

(4) Using single cell genomic techniques to understand tumor heterogeneity, to define brain tumor lineage of origin, and to improve diagnosis and treatment for brain tumor patients. The job duties include the following:

•Organize overall research plan, and design individual experiments.

•Develop and utilize novel and existing mouse models of brain tumors.

•Design and perform experiments involving ionizing radiation treatments to mice and cell lines.

•Design and perform experiments in genetically engineered mouse models of brain tumors, gene editing, molecular cloning, cell biology and biochemistry.

•Care for laboratory mice.

•Develop and utilize technology for analyzing signal transduction in vitro and vivo.

•Prepare manuscripts for scientific publication with PI supervision.

•Maintain an organized and complete electronic laboratory notebook detailing all experiments in paper and electronic formats.

•Keep PI informed by pointing out all important positive and negative results.

•Keep equipment operating by following operating instructions; troubleshooting breakdowns; maintaining supplies; performing preventive maintenance; calling for repairs.

•Maintain safe and healthy work environment by complying with regulations and following standards and procedures.

•Protect organization's value by keeping research information confidential.

•Update job knowledge by participating in educational opportunities, networking and presenting at local, national and international meetings, and reading current primary literature.

•Provide a friendly working environment and be available to help teach research technicians and other trainees laboratory techniques and scientific methodology.

Min Degree Requirements:

·Ph.D. or equivalent doctorate (e.g. Sc.D., M.D., D.V.M.).

·Should be used for post-doctoral fellows if the candidate has completed all of the requirements for a degree, but the degree has not been formally conferred; the candidate may present evidence of completion of the degree requirements, together with a statement documenting the date on which the degree is to be conferred.

Other Credential/Experiential Requirements:

The incumbent must be a true post-doctoral fellow registered with the Post Doc Office and per the following requirements:

·The term of this appointment is limited (5 years with a possible extension for an additional year)

·The appointment involves substantially full-time research or scholarship, which may include teaching responsibilities.

·The appointment is viewed as preparatory for a full time academic or research career.

·The appointment is not part of a clinical research training program, unless research training under the supervision of a senior mentor is a primary purpose of the appointment.

·The appointee works under the supervision of a scholar or a department at Duke University.

·The appointee has the freedom, and is expected to publish the results of his or her research or scholarship during the period of the appointment.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

We are not accepting applications for this job through AcademicJobsOnline.Org right now. Please apply at https://careers.duke.edu/job-invite/179228/ .
Contact: Zachary Reitman, 919-613-1181
Email: email
Postal Mail:
LSRC B225, 308 Research Drive

Durham, NC 27710
Web Page: https://radonc.duke.edu/research/reitman-lab