University of Maryland Baltimore, Pulmonary, Critical Care and Sleep Medicine
Position ID:
UMB-PCCSM-IMMUNECELLENGINEERING [#32762]
Position Title:
Postdoctoral Fellow: Immune Cell Engineering and Genetic Engineering
Position Type:
Postdoctoral
Position Location:
Baltimore, Maryland 21201, United States of America
Subject Areas:
Appl Deadline:
none (posted 2026/09/18)
Position Description:
Position Description
Postdoctoral Fellow: Immune Cell Engineering and Genetic EngineeringThe Division of Pulmonary, Critical Care and Sleep Medicine at the University of Maryland, Baltimore, School of Medicine is seeking a highly motivated Postdoctoral Researcher to design and engineer immune cells, particularly chimeric antigen receptor (CAR)-T cells, with novel functionalities, and to develop methods for monitoring engineered cell behavior, persistence, and biodistribution in real time to improve their therapeutic application in cancer.Key Responsibilities• Design and engineer immune cells, including CAR-T and other adoptive cell therapies, with novel synthetic functionalities and reporter systems.• Build and validate genetic circuits, gene-edited lines, and viral/non-viral delivery strategies.• Conduct in vitro and in vivo studies to evaluate immune cell efficacy, persistence, and safety.• Work with the imaging team to track engineered cells in vivo using PET, SPECT, and bioluminescence reporter platforms.• Collaborate with a multidisciplinary team of immunologists, bioengineers, computational scientists, and clinicians.• Present findings at internal meetings and scientific conferences and prepare manuscripts for highimpact journals.• Mentor junior researchers and contribute to a collaborative lab environment.Qualifications
• PhD in Immunology, Bioengineering, Cell Biology, Molecular Biology, or a related field.• Strong hands-on experience in cell engineering, particularly CAR-T cells or other immune cell therapies.• Proficiency in molecular biology and genetic engineering techniques, including CRISPR-based gene editing, cloning and synthetic construct design, lentiviral/retroviral vector production, and multiparametric flow cytometry.• Experience with animal models and/or immunotherapy studies.• Experience in molecular imaging or reporter gene systems is a plus.• Ability to work independently and within a collaborative team; strong communication and writing skills.Application: Interested candidates should send their CV, a cover letter outlining their research experience, interest in this position and contact information for three references to Dr. Nalinikanth Kotagiri at NKotagiri@som.umaryland.eduDesired start date: Immediately
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- Contact: Nalinikanth Kotagiri
- Email:
- Postal Mail:
- 4 Martin Luther King Junior Blvd, 4120D
Baltimore, MD 21201
https://www.medschool.umaryland.edu/medicine/divisions/division-of-pulmonary-critical-care--sleep-medicine/
- 4 Martin Luther King Junior Blvd, 4120D