University of Maryland Baltimore, Department of Microbial Pathogenesis

Position ID:University of Maryland Baltimore-Department of Microbial Pathogenesis-POSTDOCIMMUNOLOGY [#14195]
Position Title: Postdoctoral Fellow in Adjuvant Development
Position Type:Postdoctoral
Position Location:Baltimore, Maryland 21201, United States
Subject Areas: Biological Sciences
Molecular Biology
Microbiology
Immunology
Appl Deadline:2019/09/03help popup (posted 2019/08/06, listed until 2020/02/06)
Position Description:    

The Microbial Pathogenesis Department at the University of Maryland School of Dentistry is recruiting a highly motivated postdoctoral fellow to investigate the humoral and cellular immune response elicited by vaccines formulated with a novel lipid-A based adjuvant, BECC438. This project is funded by a five-year contract that has been awarded by the National Institute of Allergy and Infectious Disease (NIAID) and seeks to provide IND-enabling data packages that lead toward licensure of new vaccines. The laboratory uses a method termed bacterial enzyme combinatorial chemistry (BECC) to engineer and create bacterial lipid A structures that act as partial agonists for the innate immune receptor Toll-like receptor 4 (TLR4). BECC lipid A are screened for the ability to potentiate an immune response that, in combination with a bacterial antigen, will lead to long term protection against infectious pathogens that have a significant burden on global human health including Yersinia pestis and Shigella spp. As a part of these studies, efforts to develop new vaccine delivery methods and to further advance animal models of infection will be included. A well-suited candidate will have a strong immunology background with experience in multi-parameter flow cytometry, tissue culture, and working with mice. Preference will be given to those candidates with previous backgrounds in vaccine development, Toll-like receptor 4 (TLR4) biology, and microbiology that demonstrate a history of success with independent research. Because this person will have the opportunity to interface between government, industry, and academic institutions, the ability to maintain thorough, organized records and provide timely summaries of experiments conducted is required. The University of Maryland, Baltimore (UMB) is a world-renowned hub of microbiology and immunology research. The downtown Baltimore campus of the University of Maryland includes the Schools of Dentistry, Medicine, Law, Social Work, and others, making for a rich campus community with extensive resources. Postdoctoral resources and professional development opportunities are extensive at UMB. Centrally located, the campus is close to the excitement of Baltimore’s Inner Harbor, Camden Yards, M&T Bank Stadium, and is easily reachable by public transportation. UMB is an Equal Opportunity employer; minorities, women, individuals with disabilities, and protected veterans are encouraged to apply. To apply, please send a current, dated, and signed Curriculum Vitae, contact information for three references, and a two-page statement (maximum) of research experiences, interest, and goals to: Dr. Robert K. Ernst, PhD Professor and Vice Chair Department of Microbial Pathogenesis University of Maryland School of Dentistry e: rkernst[at]umaryland[dot]edu

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650 W. Baltimore St. 8S
Baltimore, MD 21201

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