Duke University, Biostatistics & Bioinformatics
*** this position has been closed. ***
Position Description
Postdoctoral
Associate
We
are looking for a postdoc in computational immunology to develop an in
silico model of therapeutic interventions for prevention of congenital
cytomegalovirus (cCMV) based on identified immune correlates of cCMV
transmission and placental tissue models. The model will be calibrated from a uniquely
large cohort of acutely CMV-infected pregnant women (n = 399) to predict the
outcome of a CMV vaccine in protection against placental virus transmission, as
well as the ability of maternal plasma antibodies to block virus spread at the
maternal-fetal interface. Moreover, this model can be refined through the study
of CMV replication in a placental organoid model, past and concurrent challenge
models a non-human primate model. This work will build on an existing
maternal/placental/fetal model developed by our group for CMV transmission in
the Rhesus macaque model, and extend it by including specific immune responses,
especially at the maternal-fetal interface, using neural differential equation
approaches for model calibration.
The
postdoc will also receive training in immune data science, and the analysis of
complex immunological data sets, and be part of a community of virologists,
immunologists, statisticians, and mathematicians within the Duke Center for
Human Systems Immunology.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, (including pregnancy and pregnancy related conditions), sexual orientation, or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
We are not accepting applications for this job through AcademicJobsOnline.Org right now. Please apply at https://careers.duke.edu/job-invite/238523/
.- Web Page: https://biostat.duke.edu/