University of Massachusetts Chan Medical School, Department of Population and Quantitative Health Sciences
Position ID:
Position Title:
Postdoctoral Associate
Position Type:
Open Rank
Position Location:
Worcester, Massachusetts 01605, United States of America
Subject Areas:
Appl Deadline:
2026/02/18 11:59PM
(posted 2025/08/19, listed until 2026/02/19)
(posted 2025/08/19, listed until 2026/02/19)Position Description:
Position Description
Postdoctoral Position in Computational Genomics & Bioinformatics Zhou Lab, UMass Chan Medical School About the Lab The Zhou Lab at UMass Chan Medical School (UMass Chan) develops and applies cutting edge computational and big data approaches to understand the genomics, epigenomics, and regulatory functions of noncoding RNAs in human disease. We develop computational methods and scalable pipelines to decode noncoding RNAs and their epigenetic modifications from diverse high-throughput sequencing data—advancing precision diagnostics and therapeutics. Lab Research: • AI-Driven Algorithms & Software: Develop algorithms and user-friendly software to profile RNA modifications, circular RNAs, lncRNAs, and fusion transcripts—and to predict RNA-based biomarkers and therapeutic targets. • Integrative Analysis of Multi-Omics data: Build end-to-end workflows for bulk and single-cell RNA-seq, long-read sequencing, and epigenomic assays, enabling efficient processing of large-scale, multi-omics datasets and apply them to decipher human diseases. • Translational Discovery Integrate computational findings with clinical and genetic data using machine learning/deep learning methods to identify RNA signatures of disease, guiding the development of RNA-based diagnostics and precision-medicine strategies. Research Environment: • World Class Environment: Located in the Albert Sherman Center alongside Nobel laureates Victor Ambros and Craig Mello. • Top Tier Collaborations: Close ties with leading scientists and clinicians at Harvard Medical School, MIT, and UMass Memorial Health. • Prime Location: Worcester, MA—an affordable satellite city 50 minutes from Boston by train, with a vibrant academic community and lower cost of living. • Career Development: Dr. Zhou provides tailored mentorship and resources to align your postdoctoral training with your career goals, whether academic, industry, or beyond. Required Qualifications • Ph.D. (or imminent defense) in Computational Biology, Bioinformatics, Computer Science, Applied Mathematics, Statistics, Biophysics, Biomedical Engineering, or a related field. • Strong programming skills in at least one of: Python, R, C/C++, or Perl; proficient with Unix/Linux. • Experience with machine learning, statistical modeling, or AI applications to biological data. • Familiarity with transcriptomic technologies, ideally single cell RNA seq or long read sequencing. • Demonstrated ability to conduct independent research and publish as first/co author. • Excellent communication, teamwork, and project management skills.As an equal opportunity and affirmative action employer, UMass Chan recognizes the added value of a diverse community and encourages applications from individuals with varied experiences, perspectives, and backgrounds.
Application Materials Required:
Submit the following items online at this website to complete your application:
- Cover letter
- Curriculum Vitae
- Three references (no actual letters, just names and email addresses )
And anything else requested in the position description.
Further Info:
508-856-8999
368 Plantation Street
Albert Sherman Center
Worcester, MA 01605
Albert Sherman Center
Worcester, MA 01605