University of Arkansas for Medical Sciences, Department of Biochemistry
Position ID:
Position Title:
Postdoctoral Fellow or Staff Scientist
Position Type:
Postdoctoral
Position Location:
Little Rock, Arkansas 72205, United States of America
Subject Areas:
Appl Deadline:
finished (2023/06/12, finished 2024/06/08)
Position Description:
*** this position has been closed and new applications are no longer accepted. ***
Position Description
Postdoctoral and Staff Scientist positions in Biochemistry and Structural Biology of DNA Repair
An NIH funded laboratory in the Department of Biochemistry & Molecular Biology at the University of Arkansas for Medical Sciences (UAMS) is searching for enthusiastic, talented, and team-oriented individuals for open Postdoctoral and Assistant/Associate Staff Scientist positions. The laboratory investigates the structural biology and biochemistry of DNA double strand break repair.
The candidate will be responsible for mechanistic characterization of DNA repair using structural biology, biochemical and/or biophysical approaches. The candidate will take advantage of cutting-edge capabilities in the laboratory and at UAMS, including time-resolved x-ray crystallography and Cryo-EM, rapid kinetics instrumentation, a state-of-the-art structural biology resource with extensive biophysical capabilities (e.g. SEC-MALS, ITC, CD, mass photometer, MST, fluorescence, IR) and 19 world class core facilities. The laboratory has access to EPR, XAS, NMR and regular beamtime at national synchrotron facilities.
Required Qualifications:
- PhD in Chemistry, Biochemistry, Structural Biology, Biophysics, or a related field
- Strong publication record with 1 or more first author publications in a reputable peer-reviewed journal
- Fluency in English (written and oral) and strong scientific writing skills
- Excellent problem solving, interpersonal, communication and presentation abilities
- Ability to work independently with minimal supervision and to collaborate with others
Preferred Qualifications:
- Experience with protein expression (esp. insect/mammalian) and purification
- Practical and theoretical understanding of X-ray crystallography and/or cryo-EM
- Experience with quantitative biophysical assays, enzyme kinetics (incl. transient kinetics), kinetic assay development
- Experience with high-throughput assays, quantitative ligand binding assays and/or small molecule assays
Your application should include the following:
- Cover letter
- CV with list of publications
- Statement on past research
- Contact information for 2-3 references
Application Materials Required:
Submit the following items online at this website to complete your application:
- Cover letter
- Curriculum Vitae
- Research statement
- Publication list
- Reference (actual letters acceptable but not required, just names and email addresses
)
And anything else requested in the position description.