Duke University, Biomedical Engineering

137 27726
Position ID:Duke-BME-DUKEBURSAC6 [#27726]
Position Title: Postdoctoral Associate
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27708, United States [map] sort by distance
Subject Area: Biomedical Engineering / Biomedical Engineering
Appl Deadline: (posted 2024/06/04, listed until 2024/12/04)
Position Description:    

Postdoctoral fellow in gene therapy for cardiac arrhythmias and heart failure

Postdoctoral position in gene-based therapies for cardiac arrhythmias and heart failure is immediately available in the Bursac lab. We are looking for highly motivated candidates with expertise in cell and molecular biology, single cell electrophysiology, optical mapping of action potential propagation in Langendorff-perfused hearts, and small or large animal studies of heart disease. The project involves development of novel gene-based therapies for cardiac arrhythmias and heart failure and will include work in ion channel engineering, genetic manipulations of excitable and unexcitable cells, use of iPSC technology and cell and tissue engineering to model cardiac disease in vitro, and gene therapy approaches to improve electrical conduction, prevent arrhythmias, and restore contractile function in injured or chronically diseased hearts.

Qualifications include PhD and 0-3 years of postdoctoral experience in single cell and tissue/organ cardiac electrophysiology, molecular biology, genetics, and other relevant areas of cardiovascular biomedical sciences. The ideal candidate will be highly self-motivated and possess strong training in electrophysiology, molecular biology, biochemical and histological assays, and animal studies. Experience in optical mapping, generation of transgenic animals, and genome editing (CRISPR/Cas9) is highly desirable. Postdoctoral fellows are expected to publish research findings in peer-reviewed journals, participate in conferences for the intellectual exchange of research ideas, engage in existing and new collaborations within and outside Duke University, and assist with training of undergraduate and graduate students, as needed. The environment of the Bursac group is highly interdisciplinary and provides ample opportunities for scientific growth and pursuit of both academic and industry careers. Interested candidates should send their resume, statement of research goals, and at least three names for recommendation letters to Dr. Nenad Bursac (nbursac@duke.edu.

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

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