Duke University, Biomedical Engineering

137 22834
Position ID:Duke-BME-DUKEBURSAC [#22834]
Position Title: Postdoctoral Fellow
Position Type:Postdoctoral
Position Location:Durham, North Carolina 27708, United States [map] sort by distance
Subject Area: Biomedical Engineering / Biomedical Engineering
Appl Deadline:2022/12/31 11:59PMhelp popup finished (2022/09/19, finished 2023/08/26, listed until 2024/05/31)
Position Description:    

*** this position has been closed and new applications are no longer accepted. ***

Postdoctoral Fellow Position in Cardiac Electrophysiology and Gene Therapy is immediately available in the Bursac lab (http://bursaclab.pratt.duke.edu/). We are looking for electrophysiologists with significant experience in whole-cell, cell-attached patch clamp, and sharp electrode recordings in single cells and intact tissue preparations. The project aims to develop novel gene-based therapies for cardiac arrhythmias and heart failure and will involve: performing patch clamp recordings from genetically engineered ion channels expressed in a heterologous system (HEK293 cells), viral genetic manipulations and electrophysiological recordings in primary and stem cell-derived cardiomyocytes, ion channel current and action potential recordings from adult mouse and rat cardiomyocytes isolated by Langendorff perfusion, action potential recordings from intact cardiac tissue, and optical mapping in tissue-culture and whole-heart preparations. Candidates for this position are expected to be proficient in preparing results for publications, grant applications, and conference presentations. Qualifications include PhD or post-PhD experience in single cell (patch clamp, sharp electrode) recordings, tissue/organ electrophysiology, molecular biology and biochemical techniques, and gene therapy. The ideal candidate will be highly self-motivated and possess strong training in cardiac cell and tissue electrophysiology and considerable experience in molecular biology and animal experimentation. Experience with the use of optical methods to record membrane voltage or calcium activity in cells and tissues is desirable. The candidates are expected to work well as a part of the team, engage in existing and new collaborations, and assist with training of graduate students, as needed. The research environment of the Bursac group is highly interdisciplinary and provides ample opportunities for scientific growth and pursuit of a variety of careers. Duke University is an equal opportunity employer. Interested candidates should email their resume and names of three reference writers to Dr. Nenad Bursac (nbursac@duke.edu).

Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

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